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  Indian J Med Microbiol
 

Figure 3: The dependence of dicentrics plus centric rings (Dic + CR) recording rate on Dic + CR yield (Ydr) in the sample during the fixed time microscopy for biological dosimetry. Each dot represents the values estimated during one round of fixed time microscopy. The pattern occurring at Ydr ranged from 0 to 1.6 per cell is shown in detail on the additional plot. The linear regressions were constructed separately for two distinctive intervals of Ydr: ≤1.6·per cell and >5·per cell; the latter corresponds to experimental points of homogeneous irradiations to 12 and 20 Gy. Within the latter cluster, the linear correlation was moderate: Dic + CR per min = 0.715 + 0.053 Ydr (r = 0.492), meanwhile in the main dataset, the linear fit was stronger: Dic + CR per min = 0.080 + 0.367 Ydr (r = 0,823). However, if zero values of Ydr are replaced by the mean background yield value of 0.8 × 10-3 per cell, then the dependence for Ydr ≤1.6·per cell can be effectively approximated by a power function, shown on the plot

Figure 3: The dependence of dicentrics plus centric rings (Dic + CR) recording rate on Dic + CR yield (Y<sub>dr</sub>) in the sample during the fixed time microscopy for biological dosimetry. Each dot represents the values estimated during one round of fixed time microscopy. The pattern occurring at Y<sub>dr</sub> ranged from 0 to 1.6 per cell is shown in detail on the additional plot. The linear regressions were constructed separately for two distinctive intervals of Y<sub>dr</sub>: ≤1.6·per cell and >5·per cell; the latter corresponds to experimental points of homogeneous irradiations to 12 and 20 Gy. Within the latter cluster, the linear correlation was moderate: Dic + CR per min = 0.715 + 0.053 Y<sub>dr</sub> (<i>r</i> = 0.492), meanwhile in the main dataset, the linear fit was stronger: Dic + CR per min = 0.080 + 0.367 Y<sub>dr</sub> (<i>r</i> = 0,823). However, if zero values of Y<sub>dr</sub> are replaced by the mean background yield value of 0.8 × 10<sup>-3</sup> per cell, then the dependence for Y<sub>dr</sub> ≤1.6·per cell can be effectively approximated by a power function, shown on the plot