| REVIEW ARTICLE |
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| Year : 2015 | Volume
: 6
| Issue : 1 | Page : 2 |
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Involvement of iron-containing proteins in genome integrity in arabidopsis thaliana
Caiguo Zhang
Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado, Aurora, Colorado, USA
Correspondence Address:
Caiguo Zhang
Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado, Aurora, Colorado - 80045
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2041-9414.155953
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The Arabidopsis genome encodes numerous iron-containing proteins such as iron-sulfur (Fe-S) cluster proteins and hemoproteins. These proteins generally utilize iron as a cofactor, and they perform critical roles in photosynthesis, genome stability, electron transfer, and oxidation-reduction reactions. Plants have evolved sophisticated mechanisms to maintain iron homeostasis for the assembly of functional iron-containing proteins, thereby ensuring genome stability, cell development, and plant growth. Over the past few years, our understanding of iron-containing proteins and their functions involved in genome stability has expanded enormously. In this review, I provide the current perspectives on iron homeostasis in Arabidopsis, followed by a summary of iron-containing protein functions involved in genome stability maintenance and a discussion of their possible molecular mechanisms. |
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